VERBASNOL™ For Anti-Aging Skincare - How It Works

What is Verbasnol™

If you are looking for a supplement that protects your skin at a cellular level and promotes a healthier, more youthful glow, you need one that contains Verbasnol™. 

Verbasnol™ is an incredible botanical ingredient that nourishes the skin with antioxidants and maintains the skin’s hydration and elasticity. It’s derived from Rehmannia glutinosa, a flowering broomrape and a fundamental herb of Traditional Chinese Medicine. 

In this article, you’ll learn why verbasnol is so important and why you should add it to your skincare supplements. 

Key Takeaways 

  • Verbasnol™is a botanical antioxidant derived from Rehmannia glutinosa. It protects the skin against free radical damage. 
  • As a true verbascoside, Verbasnol™ neutralizes harmful free radicals that damage skin cells and cause premature aging. 
  • It also guards against sun damage and has shown potential anti-acne and anti-yeast effects. 
  • This antioxidant can be used in topical skin care products and oral supplements. 
  • Verbasnol™ is a safe ingredient with a recommended clinical dosage of 80 mg daily. 

Featured Product

The best way to elevate your skincare is to start from the inside. Our Mytogenix Flawless RX is an NMN drink mix that harnesses the power of Verbasnol™, giving your skin resilience against external stressors. 

Coupled with other skin-enhancing ingredients like Astrion and Dermaval, this mix promotes skin’s health at the cellular level. It also combats inflammation, boosts collagen production, and hydrates. 


NMN and Verbasnol

What is Verbasnol™?

Verbasnol™ is an advanced, patented botanical that offers deep skin protection and shields skin cells from free radical damage. This botanical ingredient is an antioxidant derived from Rehmannia glutinosa, a staple herb of Traditional Chinese Medicine. 

Verbasnol™ is a true verbascoside. Verbascoside is a phenylethanoid glycoside that has various therapeutic effects, including anti-inflammatory and neuroprotective. 

How Does Verbasnol™ Work? 

Verbasnol™ is a verbascoside, a naturally occurring, plant-derived antioxidant that promotes healthy and more youthful skin.  

Antioxidants are molecules that help the body neutralize and fight off free radicals. Free radicals are harmful, unstable components that lack electrons. 

When free radicals enter the body, they steal electrons from other molecules and leave them damaged in the process. As a result, they vandalize cells and DNA, starting a chain reaction that leads to their multiplication and eventually a condition known as “oxidative stress.” 

Antioxidants (vitamins E and C) neutralize free radicals by “sacrificing” some of their own electrons. They restore the body’s balance and are mostly found in plant foods. 

If the levels of free radicals become overly high in the body, they can cause diabetes, heart disease, and even cancer. The damage can also result in premature aging, wrinkles, hyperpigmentation, loss of elasticity, and sagging skin [1, 2].   

The body produces its own antioxidant defenses to keep free radicals levels in balance. But, sometimes, exposure to prolonged stress, air pollution, and other environmental factors increases the free radicals in the body. Therefore, there’s a need to supplement with antioxidants in skincare.

While a high number of free radicals is harmful to your body, these molecules also serve important functions in the body. A good balance of free radicals allows immune cells to use them to fight infections [3]. 

The same goes for antioxidants. They are great, but only if taken at balanced levels. Too many antioxidants in the body are linked to a toxic effect and oxidative damage known as the “antioxidant paradox” [4, 5]. 

Verbasnol’s Bioactive Components 

Verbasnol™ is derived from the flowering broomrape Rehmannia glutinosa. The root of this herb contains a number of chemical constituents, including:

  • Iridoids
  • Phenethyl alcohol 
  • Glycosides 
  • Monoterpenes
  • Norcarotenoids

Research shows that this herb slows down aging in mice by keeping hematopoietic stem cells dormant and decreasing their deterioration. Because of these properties, this herb has been used to treat eczema and other dermatitis-like conditions [6]. 

Verbasnol™is a Verbascoside

Verbasnol™ is derived from the Rehmannia plant and is a true verbascoside. 

Verbascoside is a phenylethanoid glycoside isolated in 1963 from mullein. This component is an antioxidant with a natural ability to defend against sun damage and prevent aging.  

Here are some of the most important benefits of verbascoside: 

Protects Against Sun Damage  

Verbascoside is so effective in protecting the skin against sun damage that it could make a good sunscreen. Research shows that this compound has a natural SPF higher than 15 and could help repair and regenerate the cells damaged by UV radiation [7].

Exhibits Anti-Acne Activity

According to research by NuLiv Science, the creator of Verbasnol, verbacoside exhibits anti-acne activity. This compound inhibits the growth of Propionibacterium acnes (P. acnes), which causes inflammation of the skin and acne lesions. Verbacoside decreases the expression of pro-inflammatory chemokine IL-8 for its anti-inflammatory effects on the skin.   

The evaluation of 29 volunteers affected by acne showed that verbascoside (1% cream) reduces acne lesions by 40% after 4 weeks of treatment. It also provided a significant reduction in skin pigmentation and inflammation. 

Exhibits Anti-Yeast Activity 

Verbascoside may inhibit the growth of Malassezia furfur, a lipophilic yeast that irritates the skin. This yeast is known to cause atopic dermatitis, dandruff, folliculitis, and pityriasis versicolor. The minimum inhibitory concentration required to inhibit this yeast was approximately 0.6 mg/mL. 

Is Verbasnol™ Safe? 

Yes, verbasnol has been tested for safety and is well-tolerated in studies. 

The creators of the compound have tested it for safety for cosmetic and nutritional applications. 

However, there’s no doubt that we need more research on its effects as verbasnol is a rehmannia glutinosa extract titrated at 10% of verbascoside and maltodextrin. 

Most of the studies that testify about the safety of this ingredient are made on verbascoside. Verbascoside is considered an efficient and safe antioxidant [8].

The Rehmannia herb can be taken orally and is safe when used for up to 8 weeks, but dosage is important. Studies show that the most common side effects of rehmannia use are stomach problems like tenderness, nausea, and diarrhea [9]. 

Dosage and Application

The clinical dosage of Verbasnol™ is 80 mg daily. Verbasnol can be used in many preparations, but it’s most useful in: 

  • Emulsions
  • Serums
  • Creams
  • Capsules
  • Gels 


Our Mytogenix Flawless RX formula is an example of an oral skincare supplement rich in Verbasnol™. Made with patented ingredients that are proven to enhance the skin’s firmness and smoothness, this formula contains exactly 80 mg of verbasnol to be taken daily. 

Our Flawless RX formula is especially suited for people who want to add this antioxidant to their oral skincare supplements. If you are one of them, check the product here

Final Thoughts: What Makes Verbasnol™ Special?

Verbasnol™ is a natural antioxidant and a true verbascoside. 

Your skin is exposed to numerous environmental factors daily, so adding this component to your routine replenishes the skin. 

Add a supplement containing Verbasnol™ to your skincare routine to:

  • Protect your skin against sun exposure
  • Brighten the appearance of the skin
  • Replenish the skin’s antioxidant levels
  • Prevent dryness and maintain hydration

By neutralizing free radicals, this incredible botanical protects the skin and sweeps away the residual effects of sunlight, oxidative stress, and dryness. 

It maintains your skin hydrated and protects against premature skin aging and dark spots. This component has a natural SPF higher than 15 and could help regenerate UV-damaged cells. 


  1. Drăgan, S., Andrica, F., Șerban, M., & Timar, R. (2014). Polyphenols-Rich natural products for treatment of diabetes. Current Medicinal Chemistry, 22(1), 14–22.
  2. Bjelaković, G., Nikolova, D., Simonetti, R. G., & Gluud, C. (2004). Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis. The Lancet, 364(9441), 1219–1228.
  3. Hampton MB, Kettle AJ, Winterbourn CC. Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood. 1998 Nov 1;92(9):3007-17.
  4. Miller, E. R., Pastor-Barriuso, R., Dalal, D., Riemersma, R. A., Appel, L. J., & Güallar, E. (2005). Meta-Analysis: High-Dosage Vitamin E supplementation May Increase All-Cause Mortality. Annals of Internal Medicine, 142(1), 37.
  5. Henkel, R., Sandhu, I. S., & Agarwal, A. (2018). The excessive use of antioxidant therapy: A possible cause of male infertility? Andrologia, 51(1), e13162. 
  6. Bai, L., Shi, G., Yang, Y., Chen, W., Zhang, L., & Qin, C. (2018). Rehmannia glutinosa exhibits anti-aging effect through maintaining the quiescence and decreasing the senescence of hematopoietic stem cells. Animal Models and Experimental Medicine, 1(3), 194–202.
  7. Torres-Contreras, A. M., et al. (2022). Plant Secondary Metabolites against Skin Photodamage: Mexican Plants, a Potential Source of UV-Radiation Protectant Molecules. Plants, 11(2), 220. 
  8. Chun-Yang, S., Ma, Y., Tian, L., Li, J., Qiao, G., Liu, C., Cao, W., & Liang, C. (2022b). Verbascoside: an efficient and safe natural antibacterial adjuvant for preventing bacterial contamination of fresh meat. Molecules, 27(15), 4943.
  9. Poon, T. Y. C., Ong, K. L., & Cheung, B. M. Y. (2011). Review of the effects of the traditional Chinese medicine Rehmannia Six Formula on diabetes mellitus and its complications. Journal of Diabetes, 3(3), 184–200.